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Parkinson's Syndrome Parkinsonism is a miserable condition

Reviewed by
Dr. Pradip Chauhan

Definition:

Parkinsonism Parkinson's syndrome, atypical Parkinson's, or secondary Parkinson's) is a neurological syndrome characterized by tremor,hypokinesia,rigidity and postural instability.


Various conditions can cause Parkinsonism:

  • Viral encephalitis, a rare brain inflammation that follows a flu-like infection
  • Other degenerative disorders, such as dementia, multiple system atrophy, corticobasal ganglionic degeneration, and progressive supranuclear palsy
  • Structural brain disorders, such as brain tumors and strokes
  • Head injury, particularly the repeated injury that occurs in boxing (making a person punch-drunk)
  • Drugs, such as antipsychotic and the antihypertensives methyldopa and reserpine
  • Toxins, such as manganese, carbon monoxide, and methanol

Symptoms

Parkinsonism causes the same symptoms as Parkinson's disease. They include a resting tremor, stiff muscles, slow movements, and difficulty maintaining balance and walking.

The disorders that cause Parkinsonism may also cause other symptoms or variations of parkinsonian symptoms, as in the following:

  • Prominent memory loss due to dementia
  • Symptoms of parkinsonism on only one side of the body due to certain brain tumors
  • Low blood pressure and urinary problems due to multiple system atrophy
  • Inability to express or understand spoken or written language (aphasia), inability to do simple skilled tasks (apraxia), and inability to associate objects with their usual role or function (agnosia) due to corticobasal ganglionic degeneration

Parkinsonism makes life of a person miserable by impairing his movement, interfering daily activities gradually making them bad experience.


Diagnosis

Doctors ask about previous disorders, exposure to toxins, and use of drugs that could cause Parkinsonism. Brain imaging, such as computed tomography (CT) or magnetic resonance imaging (MRI), may be done to look for a structural disorder that may be causing the symptoms.

If the diagnosis is unclear, doctors may give the person levodopa, a drug used to treat Parkinson's disease, to rule out Parkinson's disease. If the drug results in clear improvement, Parkinson's disease is the likely cause.


Treatment

  • The cause is corrected or treated if possible. If a drug is the cause, stopping the drug may cure the disorder. Symptoms may lessen or disappear if the underlying disorder can be treated. The drugs used to treat Parkinson's disease (such as levodopa) are often not effective in people with Parkinsonism but can sometimes offer modest improvement.
  • Drugs are used if symptoms are bothersome. If the cause is use of antipsychotic drugs, amantadine or a drug with anticholinergic effects, may relieve symptoms.
  • The same general measures used to help people with Parkinson's disease maintain mobility and independence are useful. For example, people should remain as active as possible, simplify daily tasks, use assistive devices as needed, and take measures to make the home safe (such as removing throw rugs to prevent tripping). Physical and occupational therapists can help people implement these measures. Good nutrition is also important.

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